July 22, 2013 | Did you know that if you have Parkinson’s Disease, there are 8 kinds of medication that you should never take? If you didn’t know this, you may want to copy these down and put them into your emergency hospital kit so that if you are caught unaware, you won’t be given a dose of these that will make your PD symptoms even worse that they already are:


1. Droperiodol (Inapsine) an antidopaminergic drug used as an antiemetic and antipsychotic. Droperidol is also often used for neuroleptanalgesic anesthesia and sedation in intensive-care treatment.

2. Metoclopramide (Reglan)  A´dopaminergic´ blocker commonly used to treat nausea and vomiting, to facilitate gastric emptying in people with gastroparesis, and as a treatment for the gastric stasis often associated with migraine headaches.

3. Prochlorperazine (Copazine)  a dopamine (D2) receptor antagonist that belongs to the phenothiazine classof antipsychotic agents that are used for the antiemetic treatment of nausea and vertigo. It is also a highly potent typical antipsychotic. It is also used to treat migraine headaches. Intravenous administration can be used to treat status migrainosus.

4. Trimethobenzamide (Tigan)  is an antiemetic used to prevent nausea and vomiting. It is often prescribed for patients with gastroenteritis, medication-induced nausea, and other illnesses.

5. Promethazine (Pherergan)  is a neuroleptic medication and first-generation antihistamine of the phenothiazinefamily. The drug has strong sedative and weak antipsychotic effects. It also reduces motion sicknessand has antiemetic and anticholinergic properties. In some countries it is prescribed for insomnia when benzodiazepines are contraindicated.

6. Haloperidol (Hadol)  is a dopamine inverse agonist of the typical antipsychotic class of medications. Haloperidol is an older antipsychotic used in the treatment of schizophrenia and acutepsychotic states and delirium.

7. Reserpine (Serpasil)  A drug prescribed for high blood pressure.

8. Fluphenazine (Prolixin)   is a typical antipsychotic drug used for the treatment of psychoses such asschizophrenia, manic phases of bipolar disorder, agitation, and dementia. It belongs to the piperazine class of phenothiazines.

Thanks to Ivan Bernstein, PA-C, MPH, MSPAS at Kaiser Permanente for sharing this list with us.

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